GLP-1 medication

How long does Wegovy
stay in your system?

Wegovy contains semaglutide, the same active ingredient as Ozempic, but at higher doses approved specifically for weight management. The half-life is the same: approximately 7 days.

Based on Ozempic half-life · 7 days

2.4 mg maintenance-dose example. Enter the dose you were actually prescribed and received.

Wegovy is semaglutide dosed for chronic weight management, the same molecule as Ozempic but typically titrated to a higher maintenance dose of 2.4 mg. It shares semaglutide's roughly 7-day half-life, the longest of the common GLP-1 medications.

A single 2.4 mg dose takes about five weeks to fall to a few percent of its starting level, given the week-long half-life. With weekly dosing it builds toward steady state over roughly four to five weeks, which is why effects persist for weeks after a missed or final dose rather than stopping abruptly.